Activation of the coagulation cascade and the role of paravalvular

The Coagulation Cascade coagulation cascade The primary pathway for the initiation of blood coagulation is the tissue factor pathway Both the tissue factor and contact activation pathways coagulation cascade Heparin This combines with antithrombin-III, and force a conformational change in the compound, so that it acts at various stages of the clotting cascade to

coagulation cascade The coagulation process is characterised by a cascade of events which lead to the formation of a blood clot Proteins called clotting factors initiate reactions